Searchable abstracts of presentations at key conferences in endocrinology

ea0063p1049 | Pituitary and Neuroendocrinology 3 | ECE2019

Expression of programmed death ligand 1 (PD-L1) in human pituitary adenomas

Suteau Valentine , Collin Alexandre , Menei Philippe , Rodien Patrice , Rousselet Marie-Christine , Briet Claire

Introduction: Pituitary adenomas, second most common brain tumors, are mostly well controlled after surgery. However, some pituitary tumors present an aggressive evolution and are resistant to standard management. Immunotherapy with inhibitors of T-cell checkpoints have shown durable efficacy in a variety of malignancies. Moreover, immunotherapy has been associated with treatment-related hypophysitis, suggesting that pituitary could be a target of these treatments. Recently, i...